New York Giants at San Francisco 49ers | NFL Preview & Predictions

Dexter Moreno
Sep 20, 2023
3 min read

Thursday night football San Francisco 49ers vs New York Giants

Week 3 Thursday Night Football | New York Giants at San Francisco 49ers

The New York Giants and San Francisco 49ers play on Thursday Night, Sept. 21 in an NFL Week 3 Match-up at Levi's Stadium in California.

Match Up Predictor | NFL Predictions

The Giants are coming from the biggest comeback win in their franchise history when they beat the Arizona Cardinals 31 - 28. This caused for a celebration, but they know it won't be as easy this week against the powerhouse San Francisco 49ers (2-0).

Xavier McKinney mentioned "We can't keep having slow starts. We just have to correct it." and in order for the team to have a chance against the 49ers, Daniel Jones needs to play the way he did in that second half against Arizona.

Accomplishing that for the Giants (1-1) will be a lot harder without star running back Saquon Barkley, who will miss at least this weeks game after spraining his ankle late in the win against Arizona.

"Daniel has got his job to do, just like the running backs have their job, the receivers, the offensive line," coach Brian Daboll said. "It's individually taking care of your responsibility, whatever that may be and doing your job at a high level."

The 49ers are favorites to win this game and seeing that the Giants don't have their start running back, they will struggle to get the game started. I can see the 49ers taking the lead and there is a small chance that Daniel Jones will figure out a way to get back in the game, but it won't be enough to win.

Thursday Night Football ODDS GIANTS AT 49ERS

(8:15 p.m., Amazon Prime Video)

Moneyline: 49ers 1.18 favorites to win (bet $10 to win $11.80 total); Giants 5.25 underdogs to win (bet $10 to win $52.50 total)

Point Spread: 49ers -10.5 (49ers favored to win by more than 10.5 points, otherwise Giants cover) Total Scoring Over/Under: 44 points scored by both teams combined

Injury Report

New York Giants

NAME, POS	STATUS	DATE
Ben Bredeson G	Out	Sept 20
Andrew Thomas OT	Out	Sept 20
Wan'Dale Robinson WR	Questionable	Sept 20
Azeez Ojulari LB	Out	Sept 20
Micah McFadden LB	Questionable	Sept 20

San Francisco 49ers

NAME, POS	STATUS	DATE
Samuel Womack III CB	IR	Sept 16
Ambry Thomas CB	Questionable	Sept 18
Brandon Aiyuk WR	Questionable	Sept 20

NFL Week 3 Full Schedule

Thursday September 21st

8:15 P.M. ET

Giants at 49ers (Prime Video)

Sunday September 24th

1:00 P.M. ET

Colts at Ravens (CBS)

Titans at Browns (CBS)

Falcons at Lions (FOX)

Saints at Packers (FOX)

Texans at Jaguars (FOX)

Broncos at Dolphins (CBS)

Chargers at Vikings (FOX)

Patriots at Jets (CBS)

Bills at Commanders (CBS)

4:05 P.M. ET

Panthers at Seahawks (CBS)

4:25 P.M. ET

Cowboys at Cardinals (FOX)

Bears at Chiefs (FOX)

8:20 P.M. ET

Steelers at Raiders (NBC)

Monday September 25th

8:15 P.M. ET

Eagles at Buccaneers (ESPN/ABC)

Rams at Bengals (ESPN/ABC)

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